Hyaluronan (HA)-inspired glycopolymers as molecular tools for studying HA functions
نویسندگان
چکیده
منابع مشابه
Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA-Based Hydrogels
To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel three-dimensional (3D) hyaluronic acid (HA) hydrogel assay that provides a flexible, quantifiable, and physiologically relevant alternative to current methods. Invasion in this system reflects the prevalence of HA in connective tissues and its r...
متن کاملبررسی رفتار مکانیکی پوششهای ساده و نانوکامپوزیتی HA ،HA-TiO2 و HA-TiO2-CNT ایجاد شده به روش الکتروفورتیک
در این پژوهش پوششهای نانوکامپوزیتی هیدروکسیآپاتیت-اکسید تیتانیم (HA-TiO2) و هیدروکسیآپاتیت-اکسید تیتانیم- نانولولههای کربنی (HA-TiO2-CNT) توسط فرآیند الکتروفورتیک در ولتاژ 20 ولت و زمان 4 دقیقه بر روی زیرلایهای از جنس فولاد زنگ نزن316L ایجاد شد. به منظور ساخت سوسپانسیون پایدار از ایزوپروپانل به عنوان حلال و از تری اتانول آمین به عنوان پراکندهساز استفاده شد. ریزساختار و توزیع نانوذرات تقو...
متن کاملA modified ELISA accurately measures secretion of high molecular weight hyaluronan (HA) by Graves' disease orbital cells.
Excess production of hyaluronan (hyaluronic acid [HA]) in the retro-orbital space is a major component of Graves' ophthalmopathy, and regulation of HA production by orbital cells is a major research area. In most previous studies, HA was measured by ELISAs that used HA-binding proteins for detection and rooster comb HA as standards. We show that the binding efficiency of HA-binding protein in t...
متن کاملSynthesis and Structural Properties Characterization of HA/Alumina and HA/MgO Nanocomposite for Biomedical Applications
HAAlumina nanocomposite is biocompatible and has desirable mechanical and physical properties. Less cost, simple synthesis method, and fast production are the added advantages of this nanocomposite. Thus HA coatings on the surface of alumina substrates are used to combine excellent bioactivity of HA with superior mechanical properties of the alumina substrates. One of the elements associated wi...
متن کاملEffect of molecular weight of hyaluronic acid (HA) on viscoelasticity and particle texturing feel of HA dermal biphasic fillers
BACKGROUND Hyaluronic acid (HA) dermal biphasic fillers are synthesized for their efficacy in correcting aesthetic defects such as wrinkles, scars and facial contouring defects. The fillers consist of crosslinked HA microspheres suspended in a noncrosslinked HA. To extend the duration of HAs within the dermis and obtain the particle texturing feel, HAs are crosslinked to obtain the suitable mec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC Chemical Biology
سال: 2021
ISSN: 2633-0679
DOI: 10.1039/d0cb00223b